Artificial total hip arthroplasty for proximal femur tumors: clinical efficacy and security

doi:10.3969/j.issn.2095-4344.2014.26.003

Abstract

Abstract:

BACKGROUND: With elevated medical levels, limb salvage surgery for limb malignant tumor is valuable day by day. At present, the limb salvage surgery has substituted amputation and becomes mainstream and development direction of present surgical treatment of limb tumors. However, so far, there are no unified surgical indications for proximal femur tumor, which are controversial.
OBJECTIVE: To investigate the efficacy of artificial total hip arthroplasty combined with extended resection of tumor sections for proximal femoral bone tumors.
METHODS: Patients with proximal femoral bone tumors in the Second Xiangya Hospital of Central South University were selected and divided into control group and observation group, with 30 patients in each group. According to the disease, lesion curettage, aneurysm wall inactivation, autologous and (or) allogeneic bone, mixed bone graft and bone graft fixation were selected to treat the control group. The observation group patients received extended resection of tumor sections and total hip arthroplasty. The operative time, intraoperative blood loss, hospital stay and joint function of two groups were compared. 2 years later, patients were revisited. Metastasis and recurrence rate, death rate and quality of life of two groups were compared.
RESULTS AND CONCLUSION: There was no significant difference in intraoperative blood loss and surgery time between the two groups (P > 0.05). However, hospital stay of patients in the observation group was shorter than the control group. The excellent and good rate of recovery of joint function (83%) was higher in the observation group than in the control group (53%). The metastasis and recurrence rate within 2 years after surgery (7%) and death rate (3%) were lower in the observation group than in the control group (30%, 23%). Various indicators of quality of life of patients in the observation group were significantly better than the control group (P < 0.05). These results confirmed that artificial total hip arthroplasty in the treatment of proximal femur tumors is safe and effective.

中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程

全文链接：

Key words: femoral neoplasms, internal fixators, arthroplasty, replacement, hip, neoplasm metastasis

CLC Number:

R318

Zhou Zheng, Liu Tang . Artificial total hip arthroplasty for proximal femur tumors: clinical efficacy and security [J]. Chinese Journal of Tissue Engineering Research, 2014, 18(26): 4115-4119.

Figures/Tables 5

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